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Supplements

DHA Supplements

DHA could be a huge breakthrough in the treatment of Bipolar Disorder. It could change the whole course of treatment of this illness. Until now, the only substances that could control manic energy were very powerful drugs with many side-effects—drugs like lithium, Thorazine, anticonvulsants, and atypical antipsychotics. DHA is a nutrient found as part of omega-3 fatty acids in fish oil and other marine sources. Combining it with the psychiatric medicine can help less medicine do more work and with potentially lower side-effects.

Get the Ebook “DHA: The Bipolar Nutritional Breakthrough”.

Price: Only $4.99 with instant pdf download

DHA can be used to help stabilize mood swings, and may make it possible to take lower doses of psychiatric medications when used properly.

Get you instant PDF download of DHA: The Bipolar Nutritional Breakthrough” and find out:

  • How many milligrams of DHA to take a day
  • How to tell if an Omega-3 supplement has enough DHA
  • How to get a DHA blood test, even without a doctor or laboratory prescription
  • How to educate your doctor about DHA
  • Read about university studies and the amazing results people are getting lowering their psychiatric medications

Price: Only $4.99 with instant pdf download

DEVA Vegan Vitamins Vegan DHA (Algae) 200mg Vegan Softgels, 90-Count Bottle

About the product

  • Supplement Facts: 90 Vegan softgels/bottle, 1 Vegan softgel provides: DHA (Algae) 200 mg *
  • Clean, safe and free of ocean-borne contaminants

Price: $19.92 (approx)

Flora – DHA Vegetarian Algae Capsules – 60 count

About the product

  • Assists the development and functioning of the adult brain
  • Aids development of our nervous system during the first six months of life
  • This gluten-free unrefined oil contains no GMO material
  • Processed without hexane extraction in a GMP, Kosher facility in order to control purity
  • Vegetarian source of unrefined DHA

Price: $22.85 (approx)

Doctor’s Best Vegetarian DHA from Algae, Non-GMO, Vegan, Gluten Free, 200 mg, 60 Softgels

About the product

  • Supports memory and learning against age-related decline
  • Promotes brain and cardiovascular health at all stages of life
  • Gluten Free, Non-GMO, Vegetarian
  • Label images may vary

Price: $19.09 (approx)

Life Extension Vegetarian Sourced DHA 200 Mg, 30 softgels

About the product

  • Stimulates the production of neuronal features that underlie learning
  • Support normal mood
  • Support healthy cell signaling

Price: $10.88 (approx)

CLICK HERE TO SEE the research that shows DHA is effective for Bipolar Illness

Omega 3 Blood Test – Test the Omega 3 Levels of Your Blood In Seconds, With A Simple Finger Poke – Mail Kit and Get Results Within 5 Days of Receiving

About the product

  • Measures your blood omega 3 levels with a single drop of blood from your home.
  • Hassle-free: Send dried blood spot through regular mail and receive results via email within 5 days of OmegaQuant receiving the sample.
  • Omega 3 levels are related to cardiovascular risk, dementia risk, and how fast you will age.
  • This test has been used in large National Institutes of Health studies.
  • Test Now and then increase your score in 3 months by consuming fish oil.

Price: $47.45

CLICK HERE TO FIND OUT How to Get an Omega 3 Blood Test from your Doctor or on your own.

Now Supplements, Evening Primrose Oil 500 mg with Naturally Occurring GLA (Gamma-Linolenic Acid), 250 Softgels

Evening Primrose Oil with GLA (Gamma-Linolenic Acid) is a powerful mood elevator, and works increases levels of prostaglandin E-1 instead of serotonin

About the product

  • Servings Per Container: 83
  • Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
  • Natural color variation may occur in this product.
  • By supporting the body’s healthy immune system responses, GLA may help to maintain normal skin barrier function, as well as a healthy vascular system.
  • Healthy Skin
  • Balanced Immune Response
  • Support for Mild PMS Discomfort

Price: 12.94 (approx)

NOW Supplements, Super Primrose 1300 mg with Naturally Occurring GLA (Gamma-Linolenic Acid), 120 Softgels

About the product

  • Size: 120 Count
  • Now Foods: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please check with the manufacturer regarding warranty and support issues.

Price: 12.14 (approx)

CLICK HERE TO READ research showing evening primrose GLA effective with elevating one’s mood


Research that shows DHA is effective for Bipolar Illness

1. Some of the important research on the brain chemistry of bipolar disorder was done after the death of subjects with affective disorder. They were found to have significant deficits of DHA in the prefrontal cortex of the brain.

“Recent postmortem studies have found significant DHA deficits in the PFC (pre-frontal cortex) gray matter of patients with affective disorders. Because preclinical studies have found that brain DHA and/or its bioactive metabolites are neuroprotective, DHA deficits in PFC gray matter may increase vulnerability to the neuropathology also observed in the PFC of patients with affective disorders.”

J. Nutr. 2010 Apr; 140(4): 864–868. doi: 10.3945/jn.109.113233
DHA Deficiency and Prefrontal Cortex Neuropathology in Recurrent Affective Disorders. Robert K. McNamara.

2. When living patients with bipolar disorder had the amount of DHA in their blood cells tested, those with bipolar illness had significantly lower levels of DHA than control subjects without the illness.

“Blood plasma levels were measured in patients diagnosed with Bipolar Illness and their levels of DHA were significantly lower than the plasma of controls without the illness. Therefore DHA may provide a pharmacological basis for treatment of bipolar illness.”

J Psychiatr. Res. 2013 Mar; 47(3):337-42. doi: 10.1016/j. jpsychires.2012.11.004. Epub 2012 Dec 1. Plasma levels of n-3 fatty acids in bipolar patients: deficit restricted to DHA. Pomponi M, Janiri L, La Torre G, Di Stasio E, Di Nicola M, Mazza M, Martinotti G, Bria P, Lippa S, Natili R, Pomponi MF.

3. Bipolar patients with their first onset of manic symptoms had their DHA levels tested. Their blood cells were found to be deficient in DHA compared to healthy controls. In addition, there was no difference in EPA levels between the bipolar patients and the control subjects, leading us more to the conclusion that DHA deficiency is the prime nutritional deficiency in bipolar illness.

“Patients with their first onset of manic symptoms had their blood cells tested for DHA and were found to be significantly lower than controls without symptoms. There was no difference in EPA levels between those with manic symptoms and controls with no symptoms.”

Psychiatry Research. 2015 Dec 15; 230(2):447-53. doi: 10.1016/j. psychres.2015.09.035. Epub 2015 Oct 9. First-episode bipolar disorder is associated with erythrocyte membrane docosahexaeno ic acid deficits: Dissociation from clinical response to lithium or quetiapine. McNamara RK, Jandacek R, Tso P, Blom TJ, Welge JA, Strawn JR, Adler CM,DelBello MP, Strakowski SM.

4. Further analysis of the DHA levels showed a greater deficiency of DHA in bipolar illness but not in patients with major depression who did not have bipolar illness.

“Male and female patients with Major Depressive Disorder and Bipolar Disorder exhibit selective erythrocyte DHA deficits relative to healthy controls, and this deficit was numerically greater in Bipolar Disorder patients.”

J Affect Discord. 2010 Oct; 126(1-2) 303-311. Selective deficits in erythrocyte docosahexaenoic acid composition in adult patients with bipolar disorder and major depressive disorder. McNamara RK, Jandacek R, Rider T, Tso P, Dwivedi Y, Pandey GN.

5. An actual analysis of the diets of bipolar patients showed they consumed a diet with a lower dietary intake of DHA and other nutrients than healthy subjects.

“Bipolar individuals had significantly lower dietary intake of DHA and other key nutrients, and increased intake of saturated fats. The findings suggest that giving DHA and other nutrients may correct metabolic imbalances and may positively affect their health outcomes.”

J Psychiatr Res. 2014 Oct; 57:58-64. doi: 10.1016/j.jpsychires.2014.06.001. Epub 2014 Jun 12. Dietary intake and plasma metabolomic analysis of polyunsaturated fatty acids in bipolar subjects reveal dysregulation of linoleic acid metabolism. Evans SJ, Ringrose RN, Harrington GJ, Mancuso P, Burant CF, McInnis MG.

6. Further, in Japan, where the dietary intake of DHA is significantly higher than in the USA, levels of bipolar illness in the general population are remarkably lower.

“In Japan where DHA intake is high, the incidence of Major Depression and Bipolar Illness are many times lower than in the USA. In order to bring levels of Americans up to the level of most Japanese children would have to have a daily dose of 400-700 mg per day of pure DHA, and adults would need a dose of 700-1000 mg per day.”

Prostaglandins Leukot Essent Fatty Acids. 2009 Aug-Sep; 81(2-3):22331. doi: 10.1016/j.plefa.2009.05.017. Epub 2009 Jun 9. Evaluation of docosahexaenoic acid deficiency as a preventable risk factor for recurrent affective disorders: current status, future directions, and dietary recommendations. McNamara RK.

7. The most astounding study, though, was with pregnant women who could no longer take medication for their bipolar illness because of the risk of birth defects. Instead, they were given DHA alone, which seemed to control their symptoms.

“In our pilot study of 10 Caucasian women taking DHA while attempting to conceive (BP1 = 9, BPII = 1), age 27-42 years, DHA was well tolerated and suggests that a larger study would be feasible. The elucidation of the potential role of omega-3 fatty acids as a treatment for BD (Bipolar Disorder) requires further study. The current data are not sufficient to support a recommendation of monotherapy treatment as a substitute for standard pharmacologic treatments. However, judicious monotherapy in selected clinical situations, or adjunctive use, may be warranted pending further data from adequately powered controlled clinical trials. Our pilot trial of DHA in women who plan to stop conventional psychotropics in order to conceive suggests that such trials are feasible.”

Prostaglandins Leukot Essent Fatty Acids. 2006 Oct-Nov; 75(4-5): 315-21. Epub 2006 Aug 22. Omega-3 fatty acids in bipolar disorder: clinical and research considerations. Marangell LB, Suppes T, Ketter TA, Dennehy EB, Zboyan H, Kertz B, Nierenberg A, Calabrese J, Wisniewski SR, Sachs G.

From the award-winning book, “BIPOLAR WELLNESS: How to Recover from Bipolar Illness”

Buy Bipolar Wellness


How to Get an Omega 3 Blood Test from your Doctor or on your own

1. A prescription for a blood test to check your omega-3 levels. This will let you and your doctor know if you are deficient in omega-3 DHA and EPA. A psychiatric clinic at the University of Cincinnati has been testing all inpatient arrivals and has found 75% of them highly deficient in omega-3 molecules, DHA and EPA.

2. Here are the procedure codes your doctor will need for your prescription if he doesn’t have a list:
Current Procedural Terminology (CPT) Codes 82725, 82544 or 82492 for Blood Fatty Acid Analysis by gas-liquid chromatography (GLC)

3. After your doctor gives you a written prescription, call the laboratory you wish to use to make sure they offer the test. Check whether your insurance will cover the cost.

I would venture to say there is only a 50/50 chance that your insurance will cover this. There might also be only a 50/50 chance your doctor will order the test. If this is the case, fear not! It is time to buck the system and take your life and well-being into your own power. Consider putting out a small amount of money to order the test yourself. You don’t need a prescription. There are at least half a dozen companies that will send you a test kit with which you prick your finger. You then mail them back this blood drop for analysis; they will send you a full report of your omega-3 blood levels.”

From the award-winning book, “BIPOLAR WELLNESS: How to Recover from Bipolar Illness”

Buy Bipolar Wellness


Research showing evening primrose GLA effective with elevating one’s mood

Psychiatr Pol. 2012 Jul-Aug;46(4):585-98.
[Augmentation of antidepressants with unsaturated fatty acids omega-3 in drug-resistant depression].
Krawczyk K1, Rybakowski J.

AIM:

The aim of this paper was to evaluate the impact of augmenting administered antidepressant treatment of patients suffering from a severe episode of treatment-resistant recurrent depression or bipolar affective disorder with omega-3 fatty acids and comparing the obtained results with those achieved in the groups of patients potentiated with lithium or lamotrigine.

METHODS:

The research subjects were 21 patients diagnosed with a severe episode of treatment-resistant recurring depression in the course of recurrent depression disorders- or bipolar affective disorders. Patient eligibility included failure to respond to at least two 4-week antidepressant treatments (venlafaxine at a dose of up to 300 mg/day or paroxetine at up to 60 mg/day). The regular antidepressant treatment regimen was augmented by the “eye-q” preparation with a course of 24 capsules per day (2.2 g of EPA, 700 mg of DHA, 240 mg of GLA, from Evening Primrose Oil,40 mg of vitamin E,). The patients received the preparation for at least 4 weeks. The comparison groups consisted of the patients suffering from the current episode of severe treatment-resistant depression, treated by potentiating antidepressant treatment with lithium and lamotrigine.

CONCLUSIONS:

Augmenting a standardized antidepressant treatment with omega-3 fatty acids (and n-6 GLA Evening Primrose Oil) resulted in a marked improvement in depression symptoms measured on the Hamilton scale in the majority of patients with treatment-resistant depression. Clinical improvement upon administering fatty acids was proportional to the one achieved by potentiating therapeutic effects with lithium and lamotrigine. The use of high doses of fatty acids did not cause significant side effects.

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