A new study found that people with bipolar disorder are more likely to have changes in their genes than people who do not have the illness. These changes are called mosaic variants. Mosaic variants are new mutations that happen during development.
The study also found that people with bipolar disorder are more likely to have changes in genes that are involved in neurodevelopmental disorders (DD) and autism spectrum disorder (ASD). DDs are illnesses that affect how the brain develops. ASD is a condition that causes people to have problems with social interaction and communication.
These findings could help scientists develop new treatments for bipolar disorder. They also think that the findings could help scientists learn more about the causes of other mental illnesses.
Here is an explanation of the terms used in the article:
- Mosaic variants: These are new mutations that happen during development. They are not found in all of the cells in the body.
- Neurodevelopmental disorders: These are illnesses that affect how the brain develops. DDs can include autism spectrum disorder, intellectual disability, and cerebral palsy.
- Mitochondrial tRNA genes: These are genes that code for molecules called transfer RNA (tRNA). tRNA molecules help to make proteins
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